Shock and sorrow as Canada’s biggest co-op sold to US private equity firm Guardian (IM). IM: “Canadians who were born in the 70s grew up with MEC; I always had an MEC backpack for school, bought my winter jackets there, and when I spent serious time in the mountains in the 1990s, I couldn’t wait to make trips to the store in Calgary to gear up. There really was a co-op spirit that reflected the organization’s collectivist, hippie west coast / prairie roots. Many meaningful trips in the wilderness happened with MEC gear. Now it’s…in the hands of private equity.”
Oh wow. I covered the backs of 2 window fans with paper towels and sat them on a table in my living room. This is what happened. (Previous dips were from opening the bedroom door to allow some ventilation for a bit) pic.twitter.com/msRq13EZTR
This is interesting, but these are also aggregates, and the virus is highly capricious. For example, I would bet exposure varies by church denomination and worship style (shouting, singing). “Shopping” is also a category that’s far too broad: Air circulation patterns will differ between and within malls and small shops.
COVID-19 herd immunity: where are we? Nature. From the discussion: “With flu pandemics, herd immunity is usually attained after two to three epidemic waves, each interrupted by the typical seasonality of influenza virus and more rarely by interventions, with the help of cross-protection through immunity to previously encountered influenza viruses, and vaccines when available10. For COVID-19, which has an estimated infection fatality ratio of 0.3–1.3%1,5, the cost of reaching herd immunity through natural infection would be very high, especially in the absence of improved patient management and without optimal shielding of individuals at risk of severe complications. Assuming an optimistic herd immunity threshold of 50%, for countries such as France and the USA, this would translate into 100,000–450,000 and 500,000–2,100,000 deaths, respectively. Men, older individuals and those with comorbidities are disproportionally affected, with infection fatality ratios of 3.3% for those older than 60 years and increased mortality in individuals with diabetes, cardiac disease, chronic respiratory disease or obesity. The expected impact would be substantially smaller in younger populations.”
High potency of a bivalent human VH domain in SARS-CoV-2 animal models (preproof; PDF) Cell. From the abstract: “It potently neutralized mouse adapted SARSCoV-2 in wild type mice at a dose as low as 2 mg/kg and exhibited high prophylactic and therapeutic efficacy in a hamster model of SARS-CoV-2 infection, possibly enhanced by its relatively small size… The potent neutralization activity of VMH-Fc ab8 combined with good developability properties and cross-reactivity to SARS-CoV-2 mutants provide a strong rationale for its evaluation as a COVID-19 therapeutic.” This really does look like a novel approach (here is the English version), although let us remember the First Law of Animal Studies: “Monkeys exaggerate and mice lie.”
QAnon site shutters after reports identifying developer The Hill. For a world-girdling conspiracy theory that’s shaping up to be our next moral panic, this Jason Gelinas dude is making $3,000 a month on Patreon? That’s enough to keep him in granite counter-tops, but hardly f*ck you money for somebody who works on Wall Street, even if only in IT. Gelinas looks like an opportunistic arriviste to me. I’m still waiting for our famously free press to find out who (or what) the original Q was. Isn’t that the story here?
New Climate Maps Show a Transformed United States Pro Publica (Re Silc). “Today, the combination of truly dangerous heat and humidity [“wet bulb”] is rare. But by 2050, parts of the Midwest and Louisiana could see conditions that make it difficult for the human body to cool itself for nearly one out of every 20 days in the year. New projections for farm productivity also suggest that growing food will become difficult across large parts of the country, including the heart of the High Plains’ $35 billion agriculture industry.” Handy map:
Interesting how the Missisippi River basin transforms to a weakness from a continental strength (though I wonder how river restoration would affect humidity; I’d guess favorably). So, coastal elites doing pretty well on their project to turn flyover into a teardown! Kidding. Partly. Pretty well, except for ocean rise, of course. I wonder how long before the Irvings start selling off the Unorganized Territories in Maine to, well, gentrifiers….